Treats shipping fever, pneumonia, foot rot, calf diphtheria, metritis in beef cattle and non-lactating dairy cattle . Treats mycoplasmal swine arthritis, pasteurella pneumonia, erysipelas, acute swine dysentery in swine.
Tylosin is thought to have the same mechanism of action as ery-thromycin (binds to 50S ribosome and inhibits protein synthesis) and exhibits a similar spectrum of activity. It is a bacteriostatic antibiotic. For more specific information on or-ganisms that tylosin is usually active against. Refer to the erythromycin monography just prior to this one. Cross resistance with erythromycin occurs.
DOSAGE AND ADMINISTRATION
By Intramuscular route
Beef and non-lactating dairy cattle: 10—20mg per kg of body weight once daily, Treatment should
be continued 24 hours after symptoms of the disease have stopped. Not to exceed 5 days. Do not
inject more than 10 ml per injection site
Swine: Inject 5—13mg per kg of body weight twice daily. Treatment should be continued 24
hours after symptoms of the disease have stopped. Not to exceed 3 days. Do not inject more than
5 ml per injection site
Do not mix Tylosin injection with other injectable solutions as this may cause precipitation of the active ingredients.
Do not administer to horses or other equine species. Injection of tylosin in equines has been fatal.